As a second-group S-class submarine, the USS S-7 was laid down by Portsmouth Navy Yard in 1918 and launched two years later. It was sponsored by Mrs. Henry L. Wyman and initially had Lieutenant Commander Sherwood Picking in command. This submarine also joined Submarine Divisions 12 and 18 to embark on what was to be the longest cruise of American submarines at that time. After it departed New Hampshire, it went to Hawaii through the Panama Canal and subsequently arrived at Pearl Harbor. Finally, the submarine reached Cavite and Luzon in the Philippine Islands. The USS S-7 remained in the Philippine Islands except for yearly spring visits to Shanghai, Chefoo, Chinwangtao, Amoy, Tsingtao, and Woosung in China. Due to the high prevalence of asbestos aboard the USS S-7, the crew of this submarine was in great danger, as they would regularly inhale and ingest toxic fibers, which could, within 20 to 50 years, cause serious diseases such as lung cancer. Therefore, people who served on the USS S-7 need to keep a close eye on their health, since the risk of developing a terrible disease is very high. In 1937, the submarine was struck from the Naval Vessel Register.