The SS Isaac Shelby was a Liberty Ship built in the United States to be used for war operations during World War II. It was named in the honor of Isaac Shelby, who served as Kentucky’s first and fifth Governor. The ship was laid down in January 1944, under contract, by J.A. Jones Construction in Brunswick, Georgia and launched in March the same year. It was reassigned to the Smith & Johnson Company soon after launch. Almost a year later, the vessel struck a mine near Naples, Italy and sunk with no human casualties. The ship was salvaged in February 1948 and sold to an Italian private company for scrap.